Profile of Dr. Sanghamitra Nayak (Professor) ::

Dr. Sanghamitra Nayak
Department: Biotechnology
Designation: Professor & HOD
E-mail ID: snayak@spsiter.ac.in
Contact Number: 9437873550
Date of Birth: 28 th May, 1962
Date of joining: 2006
Status as on date of joining: Asst. Professor
Present status:Professor
Educational Qualification
Name of the Exam Board/University % of Marks Division Year of Passing
M.Sc. Botany Utkal University 65 First 1982
PhD Calcutta University - - 1990
AREA OF RESEARCH
Bioprospecting of medicinal plants and improvement of drug yielding traits through biotechnological approaches.
There is ever increasing demand for value added products of important medicinal plants like turmeric, ginger, Kaempferia, Hedychium etc in the global market. In India, the average productivity is not of desired level due to lack of remarkable effort for the improvement of the desired traits like curcumin, oleoresin, and essential oil etc, which are responsible for the drug yielding potential. Scope of improvement through conventional method is very limited due to absence of seed setting. Our group aims at systematic utilization of biotechnological approaches for genetic improvement of important medicinal plants through in vitro mutagenesis and marker assisted selection for improvement of yield and quality.
VISIT TO FOREGIN COUNTRIES
  • Bangladesh - December 1993 for paper presentation in an International Plant Tissue Culture Conference at Dhaka .
  • Hungary - July 2001 for paper presentation in World Conference on Medicinal and Aromatic Plants at Budapest .
  • Australia - August 2004 for paper presentation in an International Symposium on Horticultural Education and Training at Perth .
  • China - October 2008 for paper presentation in International Biotechnology Symposium at Dalian , China .
SPECIAL ACHIEVEMENTS
Presented a paper entitled “ Differential synthesis of essential oil in callus derived microshoots of turmeric ( Curcuma longa ) in vitro” in International Biotechnology Symposium, 2008, Dalian, China.
SEMINARS/ CONFERENCES/ WORKSHOPS/ QIP/ TRAININGS
  • International conference of Association of plant tissue culture, Oct 12-17, 2008, Dalian , China .
  • National level Seminar on “Drug Design & New Drug Discovery Techniques”, 28 th to 30 th April'06, SPS, ITER, Bhubaneswar .
Research Experience in Various Institutions

25 years of research experience in the field of Plant Biotechnology (Plant Tissue Culture, Cytogenetics, Molecular Genetics at different positions).

  • Principal Investigator (DBT) :
    Project Title: Assessment of genetic diversity in the genus Zingiber using different molecular markers and in vitro conservation of some rare and economic important taxa.

    Funding Agency : DBT, New Delhi
    Duration (From – To): October 2006 to October 2009
    Place of work: Department of Biotechnology, School of Pharmaceutical Sciences, ITER Jagamara, Po-Khandagiri, Bhubaneswar-30
  • Principal Investigator (DST) :
    Project Title:  Cytogenetic evaluation, molecular characterisation and improvement of some promising cultivars of turmeric and ginger through biotechnological methods.

    Funding Agency : Department of Science and Technology (DST), Government of India. (2002) under “SERC Fast Track Proposals for Young Scientists”
    Duration:   October 2002 ¾ October 2005
    Place of work :   Department of Bioinformatics and Biotechnology, Jaypee University of Information Technology, Waknaghat, Dist – Solan, Himachal Pradesh
  • Principal Investigator (DST) :
    Project Title:  Rapid micro-rhizome production of some commercially important cultivars of turmeric through tissue culture.
    Funding Agency : Department of Science and Technology (DST), Government of India (2002) under “Young Scientist Scheme”.
    Duration:   September 1999 ¾ March 2002
    Place of work : Aromatic and Medicinal Plants Division,Regional Research Laboratory, Bhubaneswar, Orissa.
  • Pool Officer (CSIR) :
    Project Title:  Conservation, rapid multiplication and improvement of some important species of Zingiberaceae and other economic plants through tissue culture.
    Funding Agency: Council of Scientific and Industrial Research (CSIR), New Delhi.
    Duration:   August 1996 ¾ July 1999.
    Place of work :   Aromatic and Medicinal Plants Division, Regional Research Laboratory, Bhubaneswar, Orissa.
  • Research Associate (CSIR):
    Project Title:  Micro-propagation and improvement of Cymbopogon species through tissue culture.

    Funding Agency: Council of Scientific and Industrial Research (CSIR), New Delhi.
    Duration :   July 1991 ¾ July 1996.
    Place of work :   Aromatic and Medicinal Plants Division, Regional Research Laboratory, Bhubaneswar, Orissa
  • Senior Research Fellow (CSIR) :
    Project Title :  In vitro propagation, utilisation and induction of genetic variability in species of Asparagus.
    Funding Agency: Council of Scientific and Industrial Research (CSIR), New Delhi.
    Duration:   1987 ¾ 1991.
    Place of work : Centre of Advanced Study, Department of Botany, Calcutta University, Calcutta.
  • Junior Research Fellow (UGC) :
    Project Title: Study of control of differentiated tissue of plant organs on chromosomal instability in vitro and its potentialities.
    Funding Agency: Council of Scientific and Industrial Research (CSIR), New Delhi.
    Duration: 1983 ¾ 1987.
    Place of work: Centre of Advanced Study, Department of Botany, Calcutta University, Calcutta
Teaching Experience
  • Six years of teaching experience.Three years of teaching experience (2003-2006) as Senior Lecturer and Assistant Professor in the Department of Bioinformatics, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh. Three years of teaching experience as Asst. Prof. at SPS and Centre of Biotechnology, SOA University, BBSR-751030.
SIGNIFICANT CONTRIBUTIONS
  • Mass scale propagation of elite and improved varieties of several medicinal aromatic and ornamental plants of economic importance belonging to family of Liliaceae, Gramineae and Zingiberaceae
  • Methods for controlling the instability of culture grown tissues, thereby developing relatively stable regenerants.
  • Genetic improvement of aromatic and medicinal plants through induction of somaclonal variation and mutation.
  • Study of genetic diversity using different molecular markers (RAPD, ISSR, AFLP etc.).
  • Assessment of stability of tissue culture plants through analysis of chromosome number and nuclear DNA content.
  • In vitro production of disease free planting materials, (i.e. bulbs and micro-rhizomes)
  • Plant genotyping using cytological, biochemical and molecular markers.
LIST OF PUBLICATIONS
Publications (Numbers only): 66 nos
Book: Nil                                  
Research Paper: 48        
General articles: 2
Patents: NIL Abstract: 16 (in National and International Symposium)
LIST OF PUBLICATIONS (2010-2011)
  • R K Joshi, B Kar, S Mohanty, E Subudhi and S Nayak (2011) Molecular Cloning, Characterization, and Expression Analysis of Resistance Gene Candidates in Kaempferia galanga L. Molecular Biotechnology DOI 10.1007/s12033-011-9430-6 (IF: 2.7, SCOPUS, SCI)
  • R K Joshi, B Kar, S Nayak (2011) Survey and characterization of NBS-LRR (R) genes in Curcuma longa transcriptome. Bioinformation 6(9): 360-363. (IF: 0.87, SCI, PUBMED)
  • A.P. Das , L.B. Sukla , N. Pradhan , S. Nayak (2011)Manganese biomining: A review Bioresource Technology 102(16):7381-7.
  • S Mohanty, M K Panda, S Sahoo, S Nayak (2011) Rapid and stable propagation of an economically important endemic species of Zingiber rubens Roxb. in vitro. Biologia Plantarum 55(1) 16-20.
  • S Mohanty, R Parida, S Singh, R K Joshi, E Subudhi, S Nayak (2011)  Biochemical and molecular profiling of micropropagated and conventionally grown Kaempferia galanga. Plant Cell Tissue Organ Culture. DOI: 10.1007/s11240-010-9891-5. (IF: 1.2, SCOPUS, SCI)
  • R K Joshi and Nayak S (2011) Functional characterization and signal transduction ability of the nucleotide binding site leucine rich repeats (NBS-LRR) resistance genes in plants. Genetics and Molecular Research. (Accepted, In press). (IF: 0.82, SCI, SCOPUS, PUBMED) '
  • R K Joshi, B Kar and Nayak S (2011) Exploiting EST databases for mining and characterization of short sequence repeat (SSR) markers in Catharanthus roseus L. Bioinformation. Pubmed 5(9): 378-381. (IF: 0.87, SCI, PUBMED)
  • R K Sahoo, A Kuanar, R K Joshi, A P Das, S Nayak and E Subudhi Anti-dermatophytic activity of eucalyptol rich turmeric somaclone oil against human pathogenic isolates (2011) Journal of Medicinal Plants Research 5(9), 1594-1597. (IF: 0.52, SCI, SCOPUS)
  • S Singh, B.S. Sathpathy, E Subudhi and S Nayak (2011) In vitro validation and phyto-constituent Analysis of Turmeric Extract: An Ethnological Alternative for Eye Treatment Research Journal of Medicinal plants 5(3):330-337.
  • S Singh, M K Panda, E Subudhi and S. Nayak (2010) Chemical Composition of Leaf and Rhizome Oil of an Elite Genotype Curcuma longa L. from South Eastern Ghats of OrissaJournal of Pharmacy Research, 3(7),1630-1633.
  • S Nayak ,T Kaur , S Mohanty, G Ghosh, R Choudhury, L  Acharya, E Subudhi (2010) In-vitro and ex-vitro evaluation of long-term micropropagated turmeric as analyzed through cytophotometry, phytoconstituents, biochemical and molecular markers. Plant Growth Regulations 64(1) 91-98. (IF: 2.06, SCOPUS, SCI).
  • R. K. Joshi, A. Kuanar, S. Mohanty, E. Subudhi and S. Nayak (2010). In-silico mining and characterization of EST derived microsatellites from Curcuma longa L. Bioinformation 5(3) 128-131. (IF: 0.87, SCI, PUBMED)
  • R K Joshi, S Mohanty, E Subudhi, S Nayak (2010). Isolation and characterization of NBS-LRR resistance gene candidates in Curcuma longa cv. surama. Genetics and Molecular Research 9(3): 1796-1806. (IF: 0.82, SCI, SCOPUS, PUBMED)
  • E Subudhi, S Mohanty, R K Joshi, R C Mohanty, S.Nayak (2010). Retention of drug yielding potential of long-term micropopagated gingers through periodic monitoring of genetic stability in vitro. Journal of Pharmacy Research. 3(10): 2421-2424.
  • S Singh, A Kuanar, S Mohanty, E Subudhi and S Nayak (2010) Evaluation of drug yielding potential and molecular profiling of micropropagated and conventionally grown turmeric (Curcuma longa L.). Plant Cell Tissue Organ Culture. 104(2): 263-269. (IF: 1.24, SCOPUS, SCI).
  • R K Joshi, E Subudhi, B Kar and S Nayak (2010) Comparative genetic analysis of lowland rice cultivars of India using microsatellite markers. Bioresearch Bulletin. 4:213-223.
  • R K Joshi and S Nayak (2010) Gene pyramiding- A broad-spectrum technique for developing durable stress resistance in crops. Biotechnology and Molecular Biology Reviews 5(3): 51-60.
  • R Parida, S Mohanty, A Kuanar, S Nayak (2010) Rapid multiplication and in vitro  production of  leaf  biomass  in Kaempferia  galanga through tissue culture. Electronic Journal of Biotechnology, 13(4).
  • S Mohanty, R K Joshi, E Subudhi, S Sahoo, S Nayak (2010) Assessment of genetic stability of micropropagated Curcuma caesia through cytophotometric and molecular analysis. Cytologia 75(1): 73–81. (IF: 0.2, SCOPUS, SCI).
  • E Subudhi, S. Mohanty, S Mohanty, A Kuanar, M K Panda (2010)"In Vitro Antimicrobial Study of Plant Essential Oils and Extracts". Internet journal of Microbiology. 8 (1).
PAPERS PUBLISHED IN INTERNATIONAL JOURNAL:
  • S. Nayak & S. Sen (1991). Cytological and cytophotometric analysis of direct explant and callus derived plants of Ornithogalum thyrsoides Jacq. Cytologia 56: 297-302.
  • S. Nayak & S. Sen (1992). Karyological and cytophotometric study of explants derived clones of non-polysomatic and polysomatic species of Kniphofia. Biologia Plantarum, 34(1-2) : 135-141.
  • S. Nayak & S. Sen (1992). Propagation of Ornithogalum umbellatum L. through tissue culture. Nucleus 35(1) : 74-77.
  • S. Nayak & S. Sen (1993). Growth, chromosome number and DNA content of callus tissues as influenced by different auxins. Cytobios 79 : 209-216.
  • S. Nayak & S. Sen (1995). Rapid and stable propagation of Ornithogalum umbellatum in long term culture. Plant Cell Reports 15: 150-153.
  • S. Nayak, B.K. Debata & S. Sahoo (1996). Rapid propagation of lemongrass through somatic embryogenesis in vitro. Plant Cell Reports 15: 367-370.
  • S. Nayak (1996). Plant regeneration from callus culture of Cymbopogon (Jamrosa). Journal of Herb, Spices and Medicinal Plants, 42(2): 39-46.
  • S. Nayak & S. Sen (1997). Cytological and cytophotometric analysis of callus and regenerated plant of Ornithogalum virens. Cytobios 91: 135-142.
  • S. Nayak & S. Sen (1998). Regeneration of Asparagus robustus Hort. Journal of Herb, Spices and Medicinal Plants, 54: 43-50.
  • S. Nayak & S. Sen (1998). Differential resistance of three species of Ornithogalum to extent of polyplodization in vitro. Nucleus, 41: 48-52.
  • S. Nayak (2000). In vitro multiplication and microrhizome induction in Curcuma aromatica Salisb. Plant Growth Regulation, 32: 41-47.
  • S. Nayak, B.K. Debata, H.K. Srivastava & N.S. Sangwan, 2003, Evaluation of somaclonal variants in a hybrid Cymbopogon (Jamrosa) and detection of genetic changes through RAPD.  Plant Science, 164:,1029-1035.
  • S. Nayak and P. K. Naik (2004),Factors affecting in  vitro microrhizome formation and growth in Curcuma longa L. and improved field performance of micropropagated plants. In Science Asia, 32: 31-37.
  • S. Nayak (2005). Community mobilization  for conservation and cultivation of medicinal  plants: A   case    study      in  Keonjhar District, Orissa,India inActa Horticulture 672, 291- 296.
  • P.k. naik and S. Nayak (2005).  Differential mode of plant regeneration and factors effecting in vitro bulblet prodiction in  Ornithogalum virens. in  international journal  Science Asia 31:409-414.
  • S. Nayak, P.K. Naik, L.K. Acharya, A.K. Mukherjee, P.C. Panda and P.Das (2005). Assessment of Genetic Diversity Among 16 Promising Cultivars of Ginger Using Cytological and Molecular Markers. In Z. Naturforsch  60C :485-492
  • S. Nayak, P K .Naik, L.K .Acharya, A.K. Pattnaik. (2006),  Detection and evaluation of genetic variation in 17 promising cultivars of Turmeric (Curcuma longa L.) using 4c nuclear DNA content and RAPD markers Cytologia 71:49-55.
  • M.K.Panda, S.Mohanty and E. Subudhi and S. Nayak (2007) Assessment of genetic stability of micropropagated plants of Curcuma  longa L. by cytophotometry and RAPD analyses.International journal of integrative Biology. 1:189-195.
  • S. Ghosh, E. Subudhi and S. Nayak (2008) Antimicrobial assay of Stevia rebaudiana Bertoni leaf extracts against 10 pathogens. International journal of integrative Biology. (In press)
  • Mohanty, S., Panda, M.K.,Subudhi, E., Acharya, L.K. and Nayak, S. (2008) Plant regeneration from callus culture of Curcuma aromatica Salisb. and in vitro detection of somaclonal variation through cytophotometric analysis  52(4), 783-786, Biologia Plantarum.
  • Mohanty, S., Panda, M.K., Subudhi, E.and Nayak, S. (2008) Genetic stability of micropopagated ginger derived from axillary bud through cytophotometric and RAPD analysis. 63c, 747-754, Z. Naturforsch.
  • S. Kumar, E. Subudhi, S. Nayak   and S. Sahoo (2008) Antimicrobial activity of essential oils from 15 lemongrass genotypes - a comparative assay. Internet Journal of Microbiology. 6 (1).
PAPERS PUBLISHED IN NATIONAL JOURNAL:
  • S. Nayak & S. Sen (1987). Relative cytological stability of callus and regenerated plans of Ornithogalus thyrsoides Jacq. Proc. Symp. Plant Cell & Tissue Culture of Economically Important Plants (Ed. G.M. Reddy), Hyderabad, India, pp. 265-269.
  • S. Nayak & S. Sen (1989). Cytological study of Ornithogalum thyrsoides Jacq. In vitro following gamma-ray treatment. Cell and Chromosome Research12: 45-48.
  • S. Nayak & S. Sen (1990). Differential requirement for organogenesis in two species of Kniphofia. Indian Journal of experimental Biology 28: 171-173.
  • S. Nayak & S. Sen (1992). Effect of growth regulators on direct and indirect plant regeneration in Ornithogalum Species. Plant Science Research 14(1-2): 13-16.
  • S. Nayak, S. Sahoo & B.K. Debata (1992). Differential requirement of growth regulators for plant regeneration in two species of Cymbopogon. Orissa Journal of Horticulture, 20(2): 47-50.
  • S. Nayak & S. Sen (1995). In vitro propagation of Ornithogalum umbellatum through direct organogenesis. Indian Journal of Experimental Biology, 33: 144-146.
  • S. Nayak, S. Sahoo & B.K. Debata (1995). Plant regeneration and essential oil synthesis in Lemongrass in vitro. Plant Science Research,17(1-2):29-31.
  • S. Nayak, B.K. Debata & S. Sahoo (1997). Effect of gamma irradiation on callus of Lemongrass [Cymbopogon flexuosus (Nees) Wats]. Indian Perfumer, 41(2): 41-44.
  • S. Nayak (2000). In vitro microrhizome production in four cultivars of turmeric (Curcuma longa L). Proceedings of the Centennial Conference on Spice and Aromatic Plants, held at Calicut, 20-23 September, 2000, pp. 3-9.
  • S. Nayak (2001). Turmeric in test tube, RRL Bulletin, pp.14.
  • S. Nayak (2002), High frequency in vitro microrhizome production in mango ginger (Curcuma amada Roxb.), Indian Journal of Experimental Biology, vol. 40, 230-232.
  • S. Nayak (2002).  Somatic embryogenesis and plant regeneration in a hybrid Cymbopogon (Jamrosa) Journal of Medicinal and Aromatic Plant Sciences, 24 : 669-674.
  • S. Nayak (2002) In vitro clonal multiplication and short term conservation of four promising cultivars of turmeric.  Plant Science Research, Vol, 24(1 & 2) : 7-10
  • 36 Kuanar A,  Mohanty, S., Panda, M.K., and Nayak, S. (2009)  Essential oil from leaves of micropopagated turmeric, accepted in Current science.
LIST OF PUBLISHED ABSTRACTS
Sl. No. Name of Seminar/ Symposia/ Conference Name of Sponsoring Agency Country & Date Paper contributed Authors
1. XIII Plant Tissue Culture Conference Association of Plant Tissue Culture India
(Shillong)
18-20 Oct. 1989
Propagation of Ornithogalum umbellatum through tissue culture. S. Nayak &
S. Sen
2. VII International Conference on Plant Tissue and Cell International Association of Plant Tissue Culture Netherlands (Amsterdam)
24-29 June, 1990
Cytological and Cytophotometric analysis of regenerated plants in three species of Ornithogalum S. Nayak &
S. Sen
3. International Botanical Conference CSIR, Bangladesh Bangladesh
(Dhaka)
9-12 Jan. 1991
In vitro regeneration and cytological analysis in Ornitho-galum virens S. Nayak &
S. Sen
4. 81st Session of the Indian Science Congress Indian Science Congress Association India (Goa)
January 1993
In vitro plantlet regeneration of a high yielding dwarf lemongrass mutant [Cymbopogon flexuosus (Nees) Wats.] through somatic embryogenesis S. Nayak,
B.K. Debata &
S. Sahoo
5. International Plant Tissue Culture Conference Plant Tissue Culture Association of Bangladesh Bangladesh
(Dhaka)
19-21 Dec. 1993
Plantlet regeneration from a high oil yielding dwarf lemongrass mutant in long term culture s. Nayak,
B.K. Debata &
S. Sahoo
6. 17th Annual Conference of Orissa Botanical Society Orissa Botanical Society India
(Berhampur)
27-28 Feb. 1993
In vitro plantlet regeneration of Palmarosa and Lemongrass through somatic embryogenesis S. Nayak,
B.K. Debata &
S. Sahoo
7. National Seminar on Modern Trends in Plant Resource Develop-ment, Conservation and Management Orissa Botanical Society India (Bhubaneswar)
29-30 Jan. 1994
In vitro propagation of elite Cinnamon genotype J. Pattnaik,
S. Nayak,
B.K. Debata & S. Pal
8 International Conference on Plant Tissue Culture Plant Tissue Culture Association of Bangladesh Bangladesh
(Dhaka) 9-12 Dec.1995
Rapid in vitro propagation of a high oil yielding Jamrosa S. Nayak
9 National Conference on Recent Trends in Spices and Medicinal Plant Academy of Plant Sciences, India & Spice Board, India India
(Calcutta)
2-4 April, 1998
In vitro induction of microrhizome in turmeric (Curcuma longa Linn.)  S. Nayak
10 National Seminar on potential aromatic plants of India : Exploration and Utilisation. Regional Research Laboratory, Bhubaneswar India
(Bhubaneswar)
30-31 July, 1998
Mocropropagation and microrhizome production in Mango Ginger (Curcuma aromatica Roxb.) S. Nayak
11 National Conference on Plant Biotechnology : Towards Strategic Agriculture. Central Institute of Medicinal & Aromatic Plants (CIPAM) India
(Lucknow)
15-17 March 1999
High frequency in vitro multiplication and microrhizome induction in Curcuma aromatica S. Nayak
12 International Conference on “Women :
Biotechnology, Environment and Non-Conventional Energy”.
Indian Institute of Chemical Technology (IICT) India
(Hyderabad)
17-22 Oct. 2000
Rapid production & conservation of disease-free planting materials of turmeric (Cuurcuma longa Linn) through tissue culture. S. Nayak
13 World Conference on Medicinal and Aromatic Plants Hungarian Academy of Science, Budapest Hungary
(Budapest)
8-11 July 2001
Factors regulating in vitro microrhizome production in three medicinally important species of Curcuma  S. Nayak
14 International Sumposium on Horticultural Education Extension and Training Curtin University,
Perth, Western Australia
Australia
18-21 August, 2004
Community Mobilization for Conservation and Cultivation of Medicinal Plants: A case study in Keonjhar District, Orissa, India. S. Nayak
15 National Seminar on Intellectual Property Rights in Horticultural Crops Y.S. Parmar University of Horticulture and Forestry, Solan India
12-13 Oct., 2004
Rights of farmers cultivating medicinal plants and some recommendations S.Marla, S. Nayak, P.K. Naik, R. Arrora
16 National level Sinar on “Drug Design & New Drug Discovery Techniques” AICTE Sponsored India (Orissa) 
28th to 30th April’06
Test tube turmeric S.Nayak
17 International Biotechnology Symposium-2008. DST sponsered Dalian, china Genetic stability of    micropopagated ginger cultivars as assessed through in vitro and ex vitro evaluation. E.Subudhi, S.Mohanty, M.Panda, L.K.Acharya and S.Nayak
18 International Biotechnology Symposium-2008. DST sponsered Dalian, china
12-17 Oct 2008
Genetic stability of    micropopagated ginger cultivars as assessed through in vitro and ex vitro evaluation. S.Nayak S.Mohanty,  E.Subudhi,
LIST OF ONGOING & COMPLETED PROJECTS
Title of  Project
(Ongoing)
“Assessment of genetic diversity in the genus Zingiber using different molecular markers and in vitro conservation of some rare and economic important taxa”
Funding Agency DBT, New Delhi
Duration October 2006 to October 2009
Name of Scientist Dr. S.Nayak
Project Cost     Rs. 25.04 lakhs
Title of  Project
(Completed)
“Cytogenetic evaluation, molecular characterization and improvement of some promising cultivars of turmeric and ginger through biotechnological methods”
Funding  Agency DST
Duration October 2002 to October 2005
Name of  Scientist Dr. S.Nayak
Project Cost     Rs. 9,64,000
Title of Project
(Completed)
“Rapid micro-rhizome production and improvement of some commercially important cultivars of turmeric through tissue culture”
Funding  Agency DST
Duration September 1999 to March 2002
Name of
Scientist
Dr. S.Nayak
Project Cost Rs. 6,02,963